Robin Roberts, Jamie-Lynn Sigler and Christina ApplegateRobin Roberts, Jamie-Lynn Sigler and Christina Applegate

Actresses Christina Applegate and Jamie-Lynn Sigler open up about their Terminal illness

Actresses Christina Applegate and Jamie-Lynn Sigler are coming together for the first time to open up about their health issues, multiple sclerosis.

Applegate, 52, and Sigler, 42, sat down together and talked with “Good Morning America” co-anchor Robin Roberts about the bond that developed over their shared frustrations with Applegate and Sigler’s terminal illness which was diagnosed in 2021 and diagnosed in 2001.

“She’s doing that (holding my hand) because I’m shaking,” Applegate said of Sigler, citing one of the many physical side effects of MS. “Well, it’s because I love you, but also him,” Sigler said. Also read – Kim Kardashian spotted chatting with Bianca Sensori for the first time

Christina Applegate and Jamie-Lynn Sigler
Jamie-Lynn Sigler and Christina Applegate


According to the National Institute, Sigler was 20 years old and starring in “The Sopranos” when she was diagnosed with MS, an autoimmune condition in which the body attacks the myelin that surrounds nerves, including those in the brain and spinal cord for detail of Neurological Disorders and Stroke at the National Institutes of Health.

15 years later in 2016, right after her wedding, Sigler publicly disclosed her diagnosis.

Six years later, in 2021, Christina Applegate publicly revealed her MS diagnosis, which was discovered when she became unable to walk on her own while shooting the final season of her hit Netflix show, “Dead to Me.”
“My symptoms started in the early part of 2021, and it was literally like a tingling sensation on my toes,” Applegate told Roberts during their interview at the 1 Hotel West Hollywood. “And that summer when we started shooting, I was being brought to the set in a wheelchair. Like, I couldn’t walk that far.”

Applegate credited her former co-star Selma Blair, who was diagnosed with MS in 2018, with urging her to get tested for the disease.

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